Diagnostic uncertainty during the transition to secondary progressive multiple sclerosis.

@article{Sand2014DiagnosticUD,
  title={Diagnostic uncertainty during the transition to secondary progressive multiple sclerosis.},
  author={Ilana B Katz Sand and Stephen C. Krieger and Colleen M Farrell and Aaron E. Miller},
  journal={Multiple sclerosis},
  year={2014},
  volume={20 12},
  pages={1654-7}
}
Secondary progressive multiple sclerosis (MS) is typically defined as deterioration independent of relapses for ≥ 6 months following an initial relapsing-remitting course; however, this definition is not always easily applied in clinical practice and the declaration of the change in clinical phenotype is often delayed. To identify the length of time required to re-classify relapsing-remitting MS (RRMS) patients whom have clinically transitioned to secondary progressive MS (SPMS) in clinical… CONTINUE READING
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