Diagnostic tests for antiribosomal p protein antibodies: a comparative evaluation of immunoblotting and ELISA assays.

@article{Ghirardello2002DiagnosticTF,
  title={Diagnostic tests for antiribosomal p protein antibodies: a comparative evaluation of immunoblotting and ELISA assays.},
  author={Anna Ghirardello and Laura Caponi and Franco Franceschini and Sandra Zampieri and Marzia Quinzanini and Raffaele Bendo and Stefano Bombardieri and Pier Franco Gambari and Andrea Doria},
  journal={Journal of autoimmunity},
  year={2002},
  volume={19 1-2},
  pages={71-7}
}
We compared the clinical sensitivity and specificity of three different methods for the detection of serum antiribosomal P protein (anti-P) antibodies in systemic lupus erythematosus (SLE). Sera from 60 unselected SLE patients, 100 healthy subjects and 100 patients with other rheumatic inflammatory diseases were screened for anti-P antibodies by immunoblotting (IB) on P proteins from Raji cells and by two ELISA assays, one using the C-terminal 22 aminoacid long synthetic peptide (C-22) of P… CONTINUE READING

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