Diagnostic significance of signet ring cells in fine-needle aspirates of the breast.

@article{Sethi1997DiagnosticSO,
  title={Diagnostic significance of signet ring cells in fine-needle aspirates of the breast.},
  author={Shiv. K. Sethi and Ricardo S. Cajulis and S T Gokaslan and Denise Frias-Hidvegi and Gordon H Yu},
  journal={Diagnostic cytopathology},
  year={1997},
  volume={16 2},
  pages={
          117-21
        }
}
Fine-needle aspiration (FNA) is a reliable and cost-effective procedure in the evaluation and management of breast lesions. One diagnostic dilemma that may sometimes arise is the finding of signet ring cells. The isolated finding of such cells in aspirate smears may be particularly problematic in cases of low cellularity or those with otherwise benign features. Although it is generally held that such cells are almost exclusively associated with carcinoma (particularly the lobular subtype… CONTINUE READING
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