Diagnostic role of serum glypican-3 in differentiating hepatocellular carcinoma from non-malignant chronic liver disease and other liver cancers.

@article{Tangkijvanich2010DiagnosticRO,
  title={Diagnostic role of serum glypican-3 in differentiating hepatocellular carcinoma from non-malignant chronic liver disease and other liver cancers.},
  author={Pisit Tangkijvanich and Theerawut Chanmee and Sanpoj Komtong and Varocha Mahachai and Naruemon Wisedopas and Peraphan Pothacharoen and Prachya Kongtawelert},
  journal={Journal of gastroenterology and hepatology},
  year={2010},
  volume={25 1},
  pages={129-37}
}
BACKGROUND AND AIMS The role of glypican-3 (GPC3), a novel serum marker, in differentiating hepatocellular carcinoma (HCC) from non-malignant chronic liver disease and other malignant space-occupying lesions in the liver is largely unknown. The aims of this study were to evaluate its diagnostic role and clinical correlations in patients with HCC. METHODS Six groups were studied which included 40 healthy subjects, 50 patients with chronic hepatitis (CH), 50 patients with liver cirrhosis (LC… CONTINUE READING