• Medicine
• Published in Primary care 1995

Diagnostic prediction rules: principles, requirements and pitfalls.

@article{Knottnerus1995DiagnosticPR,
  title={Diagnostic prediction rules: principles, requirements and pitfalls.},
  author={J. Andr{\'e} Knottnerus},
  journal={Primary care},
  year={1995},
  volume={22 2},
  pages={
          341-63
        }
}

• J. André Knottnerus

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This article focuses on the background, principles, requirements, and pitfalls of diagnostic prediction rules. Useful rules can only be derived from methodologically valid data bases. By considering the possibilities and limitations of prediction rules, the author concludes that these rules may support medical decision making, but cannot be a substitute for clinical skills and solid pathophysiologic knowledge.