Diagnostic performance of using one- or two-HbA1c cut-point strategies to detect undiagnosed type 2 diabetes and impaired glucose regulation within a multi-ethnic population.

@article{Mostafa2013DiagnosticPO,
  title={Diagnostic performance of using one- or two-HbA1c cut-point strategies to detect undiagnosed type 2 diabetes and impaired glucose regulation within a multi-ethnic population.},
  author={S A Mostafa and Kamlesh Khunti and Eric S. Kilpatrick and David R. Webb and B. T. Srinivasan and L J Gray and Melanie J Davies},
  journal={Diabetes & vascular disease research},
  year={2013},
  volume={10 1},
  pages={84-92}
}
INTRODUCTION We compared test performance and cost per case for strategies detecting diabetes on the oral glucose tolerance test (OGTT) using either (a) glycated haemoglobin (HbA1c) ≥ 6.5% (48 mmol/mol) or (b) two HbA1c thresholds where the first cut-point 'rules out' and the second 'rules in' diabetes. HbA1c values in between the thresholds require confirmatory glucose testing for diagnosis. MATERIALS AND METHODS We conducted an analysis of adults aged 40-75 years from the Leicester Ethnic… CONTINUE READING