Diagnostic performance of regional cerebral blood flow images derived from dynamic PIB scans in Alzheimer’s disease

@article{Peretti2019DiagnosticPO,
  title={Diagnostic performance of regional cerebral blood flow images derived from dynamic PIB scans in Alzheimer’s disease},
  author={D{\'e}bora E Peretti and David V{\'a}llez Garc{\'i}a and Fransje E. Reesink and Janine Doorduin and Bauke M. de Jong and Peter Paul de Deyn and Rudi A. J. O. Dierckx and Ronald Boellaard},
  journal={EJNMMI Research},
  year={2019},
  volume={9},
  pages={1-9}
}
BackgroundIn clinical practice, visual assessment of glucose metabolism images is often used for the diagnosis of Alzheimer’s disease (AD) through 2-[18F]-fluoro-2-deoxy-d-glucose (FDG) positron emission tomography (PET) scans. However, visual assessment of the characteristic AD hypometabolic pattern relies on the expertise of the reader. Therefore, user-independent pipelines are preferred to evaluate the images and to classify the subjects. Moreover, glucose consumption is highly correlated… CONTINUE READING