Diagnostic performance of brain MRI in pharmacovigilance of natalizumab-treated MS patients.

@article{Wattjes2016DiagnosticPO,
  title={Diagnostic performance of brain MRI in pharmacovigilance of natalizumab-treated MS patients.},
  author={Mike P. Wattjes and Martijn T. Wijburg and Anke Vennegoor and Birgit I. Witte and S. D. Roosendaal and Esther Mar{\'i}a G{\'a}mez S{\'a}nchez and Yaou Liu and Carine O Martins Jarnalo and Nancy D. Richert and Bernard Uitdehaag and Frederik Barkhof and Joep Killestein},
  journal={Multiple sclerosis},
  year={2016},
  volume={22 9},
  pages={
          1174-83
        }
}
BACKGROUND In natalizumab-treated multiple sclerosis (MS) patients, magnetic resonance imaging (MRI) is considered as a sensitive tool in detecting both MS disease activity and progressive multifocal leukoencephalopathy (PML). OBJECTIVE To investigate the performance of neuroradiologists using brain MRI in detecting new MS lesions and asymptomatic PML lesions and in differentiating between MS and PML lesions in natalizumab-treated MS patients. The secondary aim was to investigate interrater… CONTINUE READING
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