Diagnostic performance of arginase activity in colorectal cancer


Arginase activity was measured in serum and biopsy from healthy individuals and colorectal cancer patients. Arginase activity in tumor samples (87±7.7 U/g tissue) was significantly higher than in controls (40.7±3.3 U/g tissue). However, serum arginase activity did not show any significant change in both groups. Finally, the micromethod used to quantify arginase activity in this study is superior to other methods because it has increased sensitivity, requires less sample, and is less time-consuming. Arginase differences are significant, according to the t-test (P<0.05).

DOI: 10.1007/s102380200007

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@article{Rangel2002DiagnosticPO, title={Diagnostic performance of arginase activity in colorectal cancer}, author={M. del Ara Rangel and Rosa Ana Gonz{\'a}lez-Polo and A Z Caro and Eva M. del Amo and Leena Bahl Palomo and Emi Hern{\'a}ndez and Graciela Soler and Jos{\'e} M Fuentes}, journal={Clinical and Experimental Medicine}, year={2002}, volume={2}, pages={53-57} }