Diagnostic performance and predictive value of rheumatoid factor, anti-cyclic-citrullinated peptide antibodies and HLA-DRB1 locus genes in rheumatoid arthritis


BACKGROUND We evaluated the significance of the genes, defined as DRB1*04 or DRB1*01, in rheumatoid arthritis (RA) patients. We focused on the role of genetic and serologic markers to predict disease activity and destructive process of joints. METHODS Sixty patients with RA were examined. Radiographic changes were evaluated by (Larsen score) and disease… (More)
DOI: 10.1186/1755-7682-1-20

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