Diagnostic mid trimester amniocentesis: how safe?

  title={Diagnostic mid trimester amniocentesis: how safe?},
  author={John W. Seeds},
  journal={American journal of obstetrics and gynecology},
  volume={191 2},
  • John W. Seeds
  • Published 2004 in American journal of obstetrics and gynecology
OBJECTIVE Genetic mid-trimester amniocentesis is a common invasive procedure. The origin of the commonly quoted 0.5% rate of procedure-related pregnancy loss after amniocentesis is obscure and is in conflict with the only randomized prospective study that reported a procedure-related rate of loss of 1.0%. This review was performed to establish an estimate of procedure-related pregnancy loss after mid-trimester amniocentesis. The impact of placental puncture on the rate of loss and the risk of… CONTINUE READING
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