Diagnostic fragment-ion-based extension strategy for rapid screening and identification of serial components of homologous families contained in traditional Chinese medicine prescription using high-resolution LC-ESI- IT-TOF/MS: Shengmai injection as an example.

@article{Zheng2009DiagnosticFE,
  title={Diagnostic fragment-ion-based extension strategy for rapid screening and identification of serial components of homologous families contained in traditional Chinese medicine prescription using high-resolution LC-ESI- IT-TOF/MS: Shengmai injection as an example.},
  author={Chaonan Zheng and Haiping Hao and Xuan Wang and Xiaolan Wu and Guangji Wang and Guowei Sang and Yan Liang and L. X. Xie and Chunhua Xia and Xilin Yao},
  journal={Journal of mass spectrometry : JMS},
  year={2009},
  volume={44 2},
  pages={
          230-44
        }
}
The paper presents a modified and universally applicable diagnostic fragment-ion-based extension strategy (DFIBES) to efficiently process the information acquired by liquid chromatography-electrospray ionization source in combination with hybrid ion trap and high-resolution time-of-flight mass spectrometry [LC-(ESI)-IT-TOF/MS], facilitating the structural determination of serial components contained in traditional Chinese medicine prescription (TCMP). The key advantage of DFIBES is that it… CONTINUE READING
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