Diagnostic confirmation of mild traumatic brain injury by diffusion tensor imaging: a case report
@article{Krishna2012DiagnosticCO, title={Diagnostic confirmation of mild traumatic brain injury by diffusion tensor imaging: a case report}, author={Ranga Krishna and Michael Grinn and Nicholas Giordano and Magesh Thirunavukkarasu and Prasanna Tadi and Shibani Das}, journal={Journal of Medical Case Reports}, year={2012}, volume={6}, pages={66 - 66} }
IntroductionTraumatic brain injury is a form of acquired brain injury that results from sudden trauma to the head. Specifically, mild traumatic brain injury is a clinical diagnosis that can have significant effects on an individual's life, yet is difficult to identify through traditional imaging techniques.Case presentationThis is the case of a 68-year-old previously healthy African American woman who was involved in a motor vehicle accident that resulted in significant head trauma. After the…
9 Citations
Diffuse axonal injury after traumatic cerebral microbleeds: an evaluation of imaging techniques
- MedicineNeural regeneration research
- 2014
The role of imaging data showing traumatic cerebral microbleeds in the evaluation of cerebral neuronal injury and neurofunctional loss is reviewed and Cerebral microbleed is considered as an important imaging marker for diffuse axonal injury with potential relevance for prognosis.
Early Axonal Injury and Delayed Cytotoxic Cerebral Edema are Associated With Microglial Activation in a Mouse Model of Sepsis.
- BiologyShock
- 2019
It is concluded that inflammatory changes in the septic brain can be detected in real-time, and further studies are needed to understand axonal injury and the impact of inhibition of microglial activation on the development of cerebral edema.
Abcc8 (sulfonylurea receptor-1) knockout mice exhibit reduced axonal injury, cytotoxic edema and cognitive dysfunction vs. wild-type in a cecal ligation and puncture model of sepsis
- BiologyJournal of Neuroinflammation
- 2023
It is demonstrated that deletion of the SUR1 gene ameliorates CNS pathobiology in sepsis including edema, axonal injury, neuroinflammation, and behavioral deficits and suggests that brain injury may not occur merely as an extension of systemic inflammation.
Proposing a “Brain Health Checkup (BHC)” as a Global Potential “Standard of Care” to Overcome Reward Dysregulation in Primary Care Medicine: Coupling Genetic Risk Testing and Induction of “Dopamine Homeostasis”
- Psychology, MedicineInternational journal of environmental research and public health
- 2022
Continuing research is suggested into incorporating a new standard BHC coupled with qEEG/P300/Evoked Potentials and genetically guided precision induction of “dopamine homeostasis” to diagnose and treat reward dysregulation to prevent the consequences of dopamine dysregulation from being epigenetically passed on to generations of the authors' children.
Safety in Mixed Martial Arts: a 7-Year Review of Cancelled MMA Bouts in Calgary, Alberta, During the Pre-bout Medical Examination Period
- MedicineSports Medicine - Open
- 2018
Recommendations include the creation of guidelines regarding pre- and post-bout neuroimaging, the implementation of industry-wide minimum medical screening standards, the adoption of a longitudinal approach to weight monitoring, the development of competent ringside physician groups, and active oversight by the Combative Sports Commission during the matchmaking process.
Risikopatienten identifizieren und Blutungskomplikationen verhindern
- MedicineDNP - Der Neurologe und Psychiater
- 2014
ZusammenfassungTrotz prinzipiell guter Prognose können bei einem Teil der Patienten mit leichtem Schädel-Hirn-Trauma in der Akutphase Komplikationen in Form einer potenziell lebensbedrohlichen…
Editorial: NEUROTRAUMA: From Emergency Room to Back to Day-by-Day Life
- MedicineFront. Neurol.
- 2018
Diffusion Tensor Imaging Findings in Post-Concussion Syndrome Patients after Mild Traumatic Brain Injury: A Systematic Review
- MedicineFront. Neurol.
- 2016
DTI abnormalities correlate with PCS incidence and symptom severity, as well as indicate an increased risk of developing PCS after mTBI.
References
SHOWING 1-10 OF 19 REFERENCES
White Matter Abnormalities in Mild Traumatic Brain Injury: A Diffusion Tensor Imaging Study
- MedicineAmerican Journal of Neuroradiology
- 2008
Patients with mild TBI have multiple regions with reduced FA in various white matter locations and involving various fiber bundles involving a variety of fiber bundles and a minority of these fiber bundles show discontinuity on fiber tracking.
Diffusion tensor imaging in chronic head injury survivors: correlations with learning and memory indices
- Medicine, BiologyNeuroImage
- 2006
Evidence for white matter disruption in traumatic brain injury without macroscopic lesions
- Medicine, BiologyJournal of Neurology, Neurosurgery & Psychiatry
- 2006
DTI is sensitive enough to detect abnormal neural fibres related to cognitive dysfunction after nmTBI, and is seen to be coarser than in the controls in the individual magnetic resonance tractography of the corpus callosum and fornix.
MRI-DTI Tractography to Quantify Brain Connectivity in Traumatic Brain Injury
- Biology
- 2009
Preliminary analysis of DTI data suggests that it is possible to detect, localize and quantify injured regions with high statistical significance by comparing the voxellated diffusion anisotropy maps of individual TBI patients to those of the control group after all data have been normalized.
Traumatic brain injury, major depression, and diffusion tensor imaging: Making connections
- Psychology, BiologyBrain Research Reviews
- 2010
Recent neuroimaging techniques in mild traumatic brain injury.
- Psychology, MedicineThe Journal of neuropsychiatry and clinical neurosciences
- 2007
Experimental neuroimaging techniques may provide more sensitive assessment of structural and functional abnormalities following mild TBI, and particular promise is evident with fMRI, PET, and SPECT scanning, as demonstrated by associations between brain activation and clinical outcomes.
Atlas-based analysis of neurodevelopment from infancy to adulthood using diffusion tensor imaging and applications for automated abnormality detection
- MedicineNeuroImage
- 2010
MedScape
- History
- 2001
This Secret History documentary follows experts as they pick through the evidence and reveal why the plague killed on such a scale, and what might be coming next.
Acute Concussion Evaluation (ACE)
- Physician/clinician office version. Brain Inj 2006, no. CDC:2-3. http://www.cdc.gov/concussion/ headsup/pdf/ACE-a.pdf
- 2006
CDC-Injury-Concussion-Tool Kit for Physicians
- CDC-Injury-Concussion-Tool Kit for Physicians