Diagnostic characteristics of late-night salivary cortisol using liquid chromatography-tandem mass spectrometry.

@article{Zerikly2010DiagnosticCO,
  title={Diagnostic characteristics of late-night salivary cortisol using liquid chromatography-tandem mass spectrometry.},
  author={Rahfa K Zerikly and Loabat Amiri and Charles Faiman and Manjula Gupta and R J Singh and Benjamin Nutter and Laurence Kennedy and Betul A Hatipoglu and Robert J. Weil and Amir H. Hamrahian},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2010},
  volume={95 10},
  pages={
          4555-9
        }
}
OBJECTIVE The objective of the study was to describe the diagnostic performance of a commercially available late-night salivary cortisol (NSC) assay using liquid chromatography tandem mass spectrometry. METHODS We retrospectively identified 90 patients who had one or more NSC determinations: 52 patients in whom Cushing syndrome (CS) was excluded or could not be confirmed [group 1 (G1)] and 38 patients in whom CS was confirmed [group 2 (G2)]. Eighteen healthy volunteers served as controls… CONTINUE READING

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