Diagnostic and therapeutic value of apomorphine in Parkinsonian patients.

  title={Diagnostic and therapeutic value of apomorphine in Parkinsonian patients.},
  author={Jagdish Chandra Sharma and Lorna Macnamara and Mohammad Hasoon and Michael Vassallo},
  journal={International journal of clinical practice},
  volume={58 11},
Apomorphine is a dopamine agonist administered subcutaneously for the management of motor symptoms of Parkinson's disease (PD). Patients with Parkinsonian syndrome underwent an apomorphine challenge for therapeutic efficacy, a positive response being a reduction of > 15% score on motor unified PD rating scale. Of the 42 patients, aged 37-81, disease duration 12 months to 20 years, 36 had a positive response. Six non-responders were later diagnosed as non-PD as compared with only two of the 36… CONTINUE READING