Diagnostic and therapeutic relevance of NY-ESO-1 expression in oral squamous cell carcinoma.

@article{Ries2009DiagnosticAT,
  title={Diagnostic and therapeutic relevance of NY-ESO-1 expression in oral squamous cell carcinoma.},
  author={Jutta Ries and Nur Mollaoğlu and Eleftherios G Vairaktaris and Friedrich Wilhelm Neukam and Emeka Nkenke},
  journal={Anticancer research},
  year={2009},
  volume={29 12},
  pages={5125-30}
}
BACKGROUND Cancer/testis antigen 1B (NY-ESO-1) is exclusively expressed in various types of tumor but not in healthy normal tissue, except testis, and induces strong cellular and humoral immune responses. Therefore, it represents an ideal target for diagnostic and immunotherapeutic applications. The aim of the study was to investigate the expression of NY-ESO-1 in oral squamous cell carcinoma (OSCC) to determine its impact as a diagnostic parameter or a therapeutic target for oral cancer… CONTINUE READING
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