Diagnostic and prognostic value of plasma tumor M2 pyruvate kinase in periampullary cancer: evidence for a novel biological marker of adverse prognosis.

@article{Goonetilleke2007DiagnosticAP,
  title={Diagnostic and prognostic value of plasma tumor M2 pyruvate kinase in periampullary cancer: evidence for a novel biological marker of adverse prognosis.},
  author={Kolitha Sanjaya Goonetilleke and J M Mason and Priyantha Siriwardana and Nicholas K King and Michael W France and A K Siriwardena},
  journal={Pancreas},
  year={2007},
  volume={34 3},
  pages={318-24}
}
OBJECTIVE This prospective study examines the diagnostic and prognostic use of tumor-M2-pyruvate kinase (Tu-M2-PK) used in conjunction with carbohydrate antigen (CA) 19-9 in patients with subsequently histologically confirmed periampullary malignancy. METHODS Plasma Tu-M2-PK and serum CA 19-9 levels were measured at admission in a cohort of patients with suspected pancreatic cancer. Values for Tu-M2-PK and serum CA 19-9 were compared with a control group comprising jaundiced patients in whom… CONTINUE READING
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