Diagnostic and prognostic role of SCCA-IgM serum levels in hepatocellular carcinoma (HCC).

@article{Pozzan2014DiagnosticAP,
  title={Diagnostic and prognostic role of SCCA-IgM serum levels in hepatocellular carcinoma (HCC).},
  author={Caterina Pozzan and Romilda Cardin and Marika Piciocchi and Nora Cazzagon and Gemma Maddalo and Veronica Vanin and Anna Laura Giacomin and Patrizia Pontisso and Umberto Cillo and Fabio Farinati},
  journal={Journal of gastroenterology and hepatology},
  year={2014},
  volume={29 8},
  pages={1637-44}
}
BACKGROUND AND AIM The serpin squamous cell carcinoma antigen complexed with IgM (SCCA-IgM) has been reported as a promising serological marker for hepatocellular carcinoma (HCC). We aimed to further evaluate SCCA-IgM diagnostic accuracy and to determine its prognostic role. METHODS SCCA-IgM levels were determined in 327 sera obtained from 81 HCC patients, 206 cirrhotics and 40 healthy blood donors (controls). Sensitivity, specificity, correlation with clinical and tumor parameters and with… CONTINUE READING
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