Diagnostic and Statistical Manual of Mental Disorders

  title={Diagnostic and Statistical Manual of Mental Disorders},
  author={Vijay A. Mittal and Elaine F. Walker},
  journal={Psychiatry Research},


Psychosis is a common and functionally disruptive symptom of many psychiatric, neurodevelopmental, neurologic, and medical conditions and an important target of evaluation and treatment in neurologic and psychiatric practice, and current evidence-based approaches to the evaluation and management of primary and secondary psychoses are summarized.

The Semiology of Tics, Tourette's, and Their Associations

A comprehensive update on the multifarious aspects of the movement disorder and neuropsychiatry of GTS is provided and available treatment options are commented on.

Onset of psychiatric signs and impaired neurocognitive domains in inherited metabolic disorders: A case series

Clinicians should look for the co‐occurrence of age‐specific atypical signs, such as treatment resistance or worsening with psychotropic medication in the earliest stages and symptom fluctuation, confusion, catatonia, or isolated visual hallucinations.

Clinical Features of Tourette Syndrome

The clinical features of Tourette syndrome are summarized, including major diagnostic criteria, unique features of tics, and key aspects that differentiate tics from common mimics and chameleons.

Neurodevelopmental Disorders, Schizophrenia Spectrum Disorders and Catatonia: The “Iron Triangle” Rediscovered in a Case Report

This paper discusses in this paper the diagnostic, clinical and therapeutic implications of this complex relationship in an adolescent with ASD, who presented an acute psychotic onset with catatonia, associated with mixed mood symptoms.

Neurodevelopmental disorders—the history and future of a diagnostic concept

The history of the diagnostic class of neurodevelopmental disorders (NDDs) up to DSM-5 is described and how the development of genetics will transform the classification and diagnosis of NDDs is analyzed.

An Evolving Understanding of a Spectrum “Disorder”

The 2013 publication of the ​Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition ​(DSM-5) affected millions of people. Individuals who had previously received a diagnosis of

Assessment and Diagnosis of Autism and Spectrum Disorders in Children

The discussion on assessment, diagnosis, and prevalence of ASD core symptoms includes the papers by Saracino and Fombonne (Diagnostic and Assessment Issues in Autism Surveillance and Prevalence), Matson and Horowitz (Methods of Early Diagnosis and Tracking for Autism and Pervasive Developmental Disorder Not Otherwise Specified [PDDNOS]), and M Watson and Sipes (Stability of Autism Spectrum Disorders Symptoms over Time).

Fits, Tantrums, and Rages in TS and Related Disorders

This paper provides an update on aggressive symptoms in TS with focus on explosive outbursts or “rages” and self-injurious behaviors and the role of psychosocial influences.



Spontaneous movement disorders in antipsychotic-naive patients with first-episode psychoses: a systematic review

Findings support the notion that spontaneous abnormal movements are part of a neurodysfunction intrinsic to the pathogenesis of schizophrenia.

Treatment of Children and Adolescents With Tics and Tourette Syndrome

  • D. Gilbert
  • Psychology, Medicine
    Journal of child neurology
  • 2006
Achieving the most effective treatment of a child with tics is contingent on proper diagnosis of the movement disorder and thorough assessment for other problems, followed by consideration of both nonpharmacologic and pharmacologic interventions for any and all symptoms interfering with the child's function and quality of life.

Longitudinal progression of movement abnormalities in relation to psychotic symptoms in adolescents at high risk of schizophrenia.

The results are consistent with the hypothesis of shared neural circuitry for movement abnormalities and psychotic symptoms and suggest the potential value of including an assessment of motor signs in screening for psychosis risk.

Spontaneous dyskinesia in first-degree relatives of chronically ill, never-treated people with schizophrenia

Dyskinesia but not parkinsonism is more common in siblings of people with schizophrenia who have the corresponding movement disorder.

Neuromotor precursors of schizophrenia.

Group comparisons revealed a higher rate of neuromotor abnormalities in the preschizophrenia children when compared to their healthy siblings, preaffective disorder subjects, the healthy siblings of patients with affective disorder, and subjects from families with no mental illness.

Tourette syndrome and comorbid early-onset schizophrenia.

Clinical significance of neurological abnormalities in psychosis

The assessment of neurological abnormalities and extrapyramidal side-effects should figure in the assessment of any patient with psychosis, particularly at illness onset, and neurological abnormalities can inform prognostic predictions and help to identify patients with more complex future care needs.

Patient perception of tics and other movement disorders

  • A. Lang
  • Psychology, Medicine
  • 1991
A large proportion of the motor and phonic symptoms experienced by tic patients are irresistibly but purposefully executed, more akin to compulsions than to the other "involuntary" hyperkinesias with which they are commonly discussed.

Circuits and circuit disorders of the basal ganglia.

On the basis of anatomical and physiological studies and the striking success of focused surgical interventions, it seems appropriate to view these varied clinical disorders as circuit disorders, resulting from pathologic disturbances in neuronal activity throughout specific cortico-subcortical loops.