Diagnostic and Prognostic Value of SHOX2 and SEPT9 DNA Methylation and Cytology in Benign, Paramalignant and Malignant Pleural Effusions

@inproceedings{Dietrich2013DiagnosticAP,
  title={Diagnostic and Prognostic Value of SHOX2 and SEPT9 DNA Methylation and Cytology in Benign, Paramalignant and Malignant Pleural Effusions},
  author={Dimo Dietrich and Maria S Jung and Svenja Puetzer and Annette Leisse and Emily Eva Holmes and Sebastian Meller and Barbara Uhl and Philipp Schatz and Claudia Ivascu and Glen Kristiansen},
  booktitle={PloS one},
  year={2013}
}
Pleural effusions (PE) are a common clinical problem. The discrimination between benign (BPE), malignant (MPE) and paramalignant (PPE) pleural effusions is highly important to ensure appropriate patient treatment. Today, cytology is the gold standard for diagnosing malignant pleural effusions. However, its sensitivity is limited due to the sometimes low abundance of tumor cells and the challenging assessment of cell morphology in cytological samples. This study aimed to develop and validate a… CONTINUE READING