Diagnostic accuracy of bronchial brush cytology and the added value of immunohistochemistry and fluorescence in situ hybridization of pulmonary neuroendocrine tumors

@inproceedings{Reynolds2014DiagnosticAO,
  title={Diagnostic accuracy of bronchial brush cytology and the added value of immunohistochemistry and fluorescence in situ hybridization of pulmonary neuroendocrine tumors},
  author={Jordan Reynolds and Jesse S. Voss and Shannon M. Brankley and Jill M. Caudill and Michael R. Henry and Amy C. Clayton and Kevin C. Halling and Aziza Nassar},
  booktitle={CytoJournal},
  year={2014}
}
BACKGROUND Bronchial brush (BB) cytology carries low sensitivity for detecting neuroendocrine carcinomas (NECs), including typical carcinoid (TC) tumors of the lung. We aimed to investigate the detection of neuroendocrine tumors including TC through BB routine cytology cell block (CB), immunohistochemistry (IHC), and fluorescence in situ hybridization (FISH). MATERIALS AND METHODS A SNOMED search showed 187 lung biopsy or resection specimens from 2008 through 2011 containing neuroendocrine or… CONTINUE READING
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