Diagnostic Performance of Xpert MTB/RIF in Tuberculous Pleural Effusion: Systematic Review and Meta-analysis.

Abstract

A systematic review investigating the role of Xpert MTB/RIF in the diagnosis of tuberculous pleural effusion (TPE) was conducted. The pooled sensitivities and specificities of Xpert MTB/RIF were 51.4% and 98.6%, respectively, with culture used as a reference standard and 22.7% and 99.8%, respectively, with a composite reference standard (CRS) used as the benchmark. Xpert MTB/RIF has low sensitivity but excellent specificity in the diagnosis of TPE.

DOI: 10.1128/JCM.03205-15

Cite this paper

@article{Sehgal2016DiagnosticPO, title={Diagnostic Performance of Xpert MTB/RIF in Tuberculous Pleural Effusion: Systematic Review and Meta-analysis.}, author={Inderpaul Singh Sehgal and Sahajal Dhooria and Ashutosh N Aggarwal and Digambar Behera and Ritesh Agarwal}, journal={Journal of clinical microbiology}, year={2016}, volume={54 4}, pages={1133-6} }