Diagnostic Performance of Xpert MTB/RIF in Tuberculous Pleural Effusion: Systematic Review and Meta-analysis.

@article{Sehgal2016DiagnosticPO,
  title={Diagnostic Performance of Xpert MTB/RIF in Tuberculous Pleural Effusion: Systematic Review and Meta-analysis.},
  author={Inderpaul Singh Sehgal and Sahajal Dhooria and Ashutosh N Aggarwal and Digamber Behera and Ritesh Agarwal},
  journal={Journal of clinical microbiology},
  year={2016},
  volume={54 4},
  pages={1133-6}
}
A systematic review investigating the role of Xpert MTB/RIF in the diagnosis of tuberculous pleural effusion (TPE) was conducted. The pooled sensitivities and specificities of Xpert MTB/RIF were 51.4% and 98.6%, respectively, with culture used as a reference standard and 22.7% and 99.8%, respectively, with a composite reference standard (CRS) used as the benchmark. Xpert MTB/RIF has low sensitivity but excellent specificity in the diagnosis of TPE. 
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