Diagnostic, Prognostic, and Predictive Utility of Recurrent Somatic Mutations in Myeloid Neoplasms.

@article{Patel2017DiagnosticPA,
  title={Diagnostic, Prognostic, and Predictive Utility of Recurrent Somatic Mutations in Myeloid Neoplasms.},
  author={Umang Patel and Rajyalakshmi Luthra and L Jeffrey Medeiros and Keyur Pravinchandra Patel},
  journal={Clinical lymphoma, myeloma & leukemia},
  year={2017},
  volume={17S},
  pages={
          S62-S74
        }
}
The classification and risk stratification of myeloid neoplasms, including acute myeloid leukemia, myelodysplastic syndromes, myelodysplastic syndromes/myeloproliferative neoplasms, and myeloproliferative neoplasms, have increasingly been guided by molecular genetic abnormalities. Gene expression analysis and next-generation sequencing have led to the ever increasing discovery of somatic gene mutations in myeloid neoplasms. Mutations have been identified in genes involved in epigenetic… CONTINUE READING
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