Diagnosis of ulcerative colitis before onset of inflammation by multivariate modeling of genome-wide gene expression data.

@article{Olsen2009DiagnosisOU,
  title={Diagnosis of ulcerative colitis before onset of inflammation by multivariate modeling of genome-wide gene expression data.},
  author={J\orgen Olsen and Thomas Gerds and Jakob Benedict Seidelin and Cl{\'a}udio Csillag and Jacob Tveiten Bjerrum and Jesper Thorvald Troelsen and Ole Haagen Nielsen},
  journal={Inflammatory bowel diseases},
  year={2009},
  volume={15 7},
  pages={
          1032-8
        }
}
BACKGROUND Endoscopically obtained mucosal biopsies play an important role in the differential diagnosis between ulcerative colitis (UC) and Crohn's disease (CD), but in some cases where neither macroscopic nor microscopic signs of inflammation are present the biopsies provide only inconclusive information. Previous studies indicate that CD cannot be diagnosed by molecular and histological diagnostic tools using colonic biopsies without microscopic signs of inflammation, but it is unknown if… CONTINUE READING
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