Diagnosis of smear-negative tuberculosis is greatly improved by Xpert MTB/RIF

@inproceedings{Lombardi2017DiagnosisOS,
  title={Diagnosis of smear-negative tuberculosis is greatly improved by Xpert MTB/RIF},
  author={Giulia Lombardi and Valentina dI Gregori and Nicol{\`o} Girometti and Manuela Tadolini and Francesco Bisognin and Paola Dal Monte},
  booktitle={PloS one},
  year={2017}
}
BACKGROUND Diagnosis of pulmonary (PTB) and extra-pulmonary tuberculosis (EPTB) in smear-negative patients can be difficult. We assessed retrospectively the performance of Xpert MTB/RIF system (Xpert, Cepheid) in diagnosing smear-negative tuberculosis (TB), which represents the most common form of TB in a low incidence setting. METHODS Performance of Xpert was compared to acid-fast microscopic examination using Ziehl-Neelsen (ZN) stain in patients with culture-confirmed TB. RESULTS 386… CONTINUE READING
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