Diagnosis of primary human herpesvirus 6 and 7 infections in febrile infants by polymerase chain reaction.

@article{Clark1997DiagnosisOP,
  title={Diagnosis of primary human herpesvirus 6 and 7 infections in febrile infants by polymerase chain reaction.},
  author={Duncan A. Clark and Ian M. Kidd and Kathryn E Collingham and Mikela Tarlow and T Ayeni and Andrew F. Riordan and Paul D. Griffiths and Vincent C Emery and Deenan Pillay},
  journal={Archives of disease in childhood},
  year={1997},
  volume={77 1},
  pages={42-5}
}
Primary human herpesvirus 6 (HHV-6) and 7 (HHV-7) infections were identified in febrile children by qualitative and quantitative polymerase chain reaction (PCR) assays. Diagnosis was based on the differential detection of viral DNA in peripheral blood mononuclear cells (PBMC), but not in saliva. Six of 41 febrile infants, but none of seven non-febrile controls, were identified with primary infections (three HHV-6, three HHV-7). These children had significantly higher viral loads in PBMC (HHV-6… CONTINUE READING

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