Diagnosis of peritonitis using near-infrared optical imaging of in vivo labeled monocytes-macrophages.

@article{Lisy2006DiagnosisOP,
  title={Diagnosis of peritonitis using near-infrared optical imaging of in vivo labeled monocytes-macrophages.},
  author={M. R. Lisy and Elisabeth Sch{\"u}ler and Frank Lehmann and Peter Dr. Czerney and Werner Alois Kaiser and I. Hilger},
  journal={Journal of biomedical optics},
  year={2006},
  volume={11 6},
  pages={
          064014
        }
}
Peritonitis is an inflammatory process characterized by massive monocytes-macrophages infiltration. Since early diagnosis is important for a successful therapeutic outcome, the feasibility for a selective labeling and imaging of macrophages for highly sensitive optical imaging was assessed. After in vitro incubation of mouse macrophages J774A.1 with the far-red/near-infrared fluorochrome DY-676, distinct fluorescence intensities (1026+/-142 a.u.) were detected as compared to controls (552+/-54… CONTINUE READING

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