Diagnosis of hemochromatosis.

  title={Diagnosis of hemochromatosis.},
  author={Lawrie William Powell and Donald K. George and Sharon M McDonnell and Kris V. Kowdley},
  journal={Seminars in gastrointestinal disease},
  volume={13 2},
If untreated, hemochromatosis can cause serious illness and early death, but the disease is still substantially under-diagnosed. The cornerstone of screening and case detection is the measurement of serum transferrin saturation and the serum ferritin level. Once the diagnosis is suspected, physicians must use serum ferritin levels and hepatic iron stores on liver biopsy specimens to assess patients for the presence of iron overload. Liver biopsy is also used to establish the presence or absence… CONTINUE READING