Diagnosis of gestational, congenital, and placental malaria in Colombia: comparison of the efficacy of microscopy, nested polymerase chain reaction, and histopathology.

@article{Campos2011DiagnosisOG,
  title={Diagnosis of gestational, congenital, and placental malaria in Colombia: comparison of the efficacy of microscopy, nested polymerase chain reaction, and histopathology.},
  author={Iv{\'o}n M Campos and Mary Luz Uribe and Carolina Cuesta and Alexander Franco-Gallego and Jaime Carmona-Fonseca and Amanda Maestre},
  journal={The American journal of tropical medicine and hygiene},
  year={2011},
  volume={84 6},
  pages={929-35}
}
The technical capability of different methods to diagnose Plasmodium in maternal peripheral blood, placenta, and umbilical cord blood has not been assessed in Colombia and seldom explored in other malaria-endemic regions. We designed a study to compare the technical and the operational-economical performances of light microscopy (LM), nested polymerase chain reaction (nPCR), and histopathology (HP). In maternal blood, LM had 41% sensitivity and 100% specificity and in placental blood, 35% and… CONTINUE READING