Diagnosis of feline infectious peritonitis: Update on evidence supporting available tests

@article{Tasker2018DiagnosisOF,
  title={Diagnosis of feline infectious peritonitis: Update on evidence supporting available tests},
  author={S{\'e}verine Tasker},
  journal={Journal of Feline Medicine and Surgery},
  year={2018},
  volume={20},
  pages={228 - 243}
}
  • S. Tasker
  • Published 2018
  • Medicine
  • Journal of Feline Medicine and Surgery
Practical relevance: Feline coronavirus (FCoV) infection is very common in cats, usually causing only mild intestinal signs such as diarrhoea. Up to 10% of FCoV infections, however, result in the fatal disease feline infectious peritonitis (FIP). Clinical challenges: Obtaining a definitive diagnosis of FIP based on non-invasive approaches is difficult. Confirmation of the disease relies on finding appropriate cytological or histopathological changes in association with positive immunostaining… Expand
Streptococcus equi subsp. zooepidemicus finding in confirmed feline infectious peritonitis cat patient
TLDR
It was showed that viral infection followed by bacterial infection could be fatal and untreatable and clinicians may consider SEZ infection in cat with respiratory disorder followed by thoracic effusion besides FIP. Expand
Update on feline infectious peritonitis
TLDR
This article provides an update regarding diagnosing cases of FIP and guidance on current treatment recommendations, as well as providing an update on how to identify and treat feline infectious peritonitis. Expand
Feline Infectious Peritonitis: Update on Pathogenesis, Diagnostics, and Treatment.
  • M. Kennedy
  • Medicine
  • The Veterinary clinics of North America. Small animal practice
  • 2020
TLDR
The developments in the understanding of this disease as well as the progress in diagnosis and treatment are discussed. Expand
A retrospective study of clinical and laboratory features and treatment on cats highly suspected of feline infectious peritonitis in Wuhan, China
TLDR
The study highlights the diverse range of clinical manifestations by clinicians in diagnosing this potentially fatal disease and suggests GS-441524 and GC376 were efficient for the treatment of FIP-suspected cats. Expand
Diagnosis of non-effusive feline infectious peritonitis by reverse transcriptase quantitative PCR from mesenteric lymph node fine-needle aspirates
TLDR
In cases with a high index of suspicion of disease, RT-qPCR targeting FCoV in MLN FNA can provide important information to support the ante-mortem diagnosis of non-effusive FIP. Expand
Current status on treatment options for feline infectious peritonitis and SARS-CoV-2 positive cats
TLDR
An update on the current status of therapeutics for FIP is provided and due to interest in coronaviruses resulting from the current human pandemic, this review provides information on domesticated cats identified as SARS-CoV-2 positive. Expand
Feline Coronaviruses Identified in Feline Effusions in Suspected Cases of Feline Infectious Peritonitis
TLDR
Ninety-five effusion samples were collected from cats with suspected feline infectious peritonitis in northern Taiwan; these samples showed a 47.4% feline coronavirus (FCoV) positivity rate on immunofluorescence staining and RT-PCR, and no significant association was found between the positive rates and sex or breed. Expand
Epicarditis in a cat caused by feline infectious peritonitis virus: case report
TLDR
Epicarditis should be considered a differential diagnosis of cardiac diseases in Feline Medicine because it is the second report of epicarditis due to FIPV in a cat. Expand
Immunohistochemical studies on meningoencephalitis in feline infectious peritonitis (FIP)
TLDR
In one case which was negative for FIPV antigen, severe inflammation predominantly consisting of CD20-positive B lymphocytes was observed in the leptomeninges and subventricles, accompanied with diffuse proliferation of gemistocytic astrocytes. Expand
Detection of Feline Coronavirus in Feline Effusions by Immunofluorescence Staining and Reverse Transcription Polymerase Chain Reaction
TLDR
The latest epidemiological status of FCoV infection in the northern part of Taiwan among sick cats is demonstrated and comparisons of Taiwan and other countries are presented. Expand
...
1
2
3
4
...

References

SHOWING 1-10 OF 93 REFERENCES
Performances of different diagnostic tests for feline infectious peritonitis in challenging clinical cases
TLDR
This study aimed to assess the performances of tests carried out in vivo or at postmortem examination in challenging cases in which FIP was confirmed or excluded based on IHC or on adequate follow-up. Expand
Feline infectious peritonitis. ABCD guidelines on prevention and management
TLDR
The clinical picture of FIP is highly variable, depending on the distribution of the vasculitis and pyogranulomatous lesions, and there are no controlled studies to prove any beneficial effect of corticosteroids. Expand
[Clinical symptoms and diagnosis of feline infectious peritonitis].
TLDR
Body effusions from 197 cats and blood serum samples from 252 cats, where Feline Infectious Peritonitis (FIP) was part of the differential diagnosis, were analysed and the rivalta test was highly sensitive for FIP. Expand
Investigation into the utility of an immunocytochemical assay in body cavity effusions for diagnosis of feline infectious peritonitis
TLDR
The diagnostic utility of this test proved to be insufficient and positive ICC results should be interpreted with caution, and ICC of effusion samples currently cannot be recommended to confirm a suspicion of FIP. Expand
Diagnostic Features of Clinical Neurologic Feline Infectious Peritonitis
TLDR
Most cats with neurologic and ocular forms of FIP had patchy, focal lesions, suggesting that recently developed technologies described in this report may be useful for evaluation of cats with suspected FIP. Expand
Utility of an immunocytochemical assay using aqueous humor in the diagnosis of feline infectious peritonitis
TLDR
The diagnostic utility of an immunocytochemical assay in aqueous humor of cats suspected of having FIP is limited and false‐positive results occurred and specificity is most important in the diagnosis of FIP. Expand
Comparison of Different Tests to Diagnose Feline Infectious Peritonitis
TLDR
Positive and negative predictive values of Rivalta's test, a test that distinguishes between exudates and transudates, and immunofluorescence staining of coronavirus antigen in macrophages were investigated, and diagnostic assays on the fluid in cats with body effusion had good predictive values. Expand
Value of α1-acid glycoprotein in the diagnosis of feline infectious peritonitis
TLDR
Levels of AGP greater than 1.5 g/litre in serum, plasma or effusion samples were found to be of value in distinguishing field cases of FIP from cats with similar clinical signs and differentiated these two groups of cats more effectively than the albumin:globulin ratio. Expand
Detection of feline coronavirus spike gene mutations as a tool to diagnose feline infectious peritonitis
TLDR
A positive result is highly indicative of the presence of FIP, but as none of the control cats tested positive by RT-nPCR, it was not possible to confirm that the FCoV mutant described can only be found in cats with FIP. Expand
Diagnostic utility of cerebrospinal fluid immunocytochemistry for diagnosis of feline infectious peritonitis manifesting in the central nervous system
TLDR
CSF ICC is a highly sensitive test for ante-mortem diagnosis of FIP manifesting in the CNS, however, CNS ICC specificity is too low to confirm FIP and the method should only be applied in conjunction with other features such as CSF cytology. Expand
...
1
2
3
4
5
...