Diagnosis of cirrhosis in patients with chronic hepatitis C genotype 4: Role of ABCB11 genotype polymorphism and plasma bile acid levels.

@article{Besheer2018DiagnosisOC,
  title={Diagnosis of cirrhosis in patients with chronic hepatitis C genotype 4: Role of ABCB11 genotype polymorphism and plasma bile acid levels.},
  author={T Besheer and Mona M. Arafa and Mohamed Diaa Abd El-Maksoud and H Elalfy and Amany Me Hasson and Khaled refaat Zalata and Wagdi Fawzi Elkashef and Heba El-shahawy and Doaa Raafat and Wafaa Elemshaty and Eman Tayae Elsayed and Hosam Zaghloul and Ahmed Aka Razek and Mahmoud El-Bendary},
  journal={The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology},
  year={2018},
  volume={29 3},
  pages={
          299-307
        }
}
BACKGROUND/AIMS Chronic hepatitis C (CHC)-related mortality generally results from cirrhosis and subsequent complications. We aimed to investigate the potential role of plasma bile acid levels and ABCB11 1331T > C (V444A, rs2287622) (ATP-binding cassette subfamily B, member 11) gene polymorphism in fibrosis prediction in CHC genotype 4 patients. MATERIALS AND METHODS This case control study included 85 healthy control and the following 225 subjects: 170 adult patients infected with hepatitis… CONTINUE READING

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