Diagnosis of bladder cancer and prediction of survival by urinary metabolomics

  title={Diagnosis of bladder cancer and prediction of survival by urinary metabolomics},
  author={Xing Yu Jin and Seok Joong Yun and Pildu Jeong and Isaac Yi Kim and Wun Jae Kim and Sunghyouk Park},
Bladder cancer (BC) is a common cancer but diagnostic modalities, such as cystoscopy and urinary cytology, have limitations. Here, high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry (HPLC-QTOFMS) was used to profile urine metabolites of 138 patients with BC and 121 control subjects (69 healthy people and 52 patients with hematuria due to non-malignant diseases). Multivariate statistical analysis revealed that the cancer group could be clearly distinguished from… CONTINUE READING


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