Diagnosis of arthritis using near-infrared fluorochrome Cy5.5.

@article{Hansch2004DiagnosisOA,
  title={Diagnosis of arthritis using near-infrared fluorochrome Cy5.5.},
  author={Andreas Hansch and Oliver Frey and I. Hilger and Dieter Sauner and Michael Haas and Dirk Schmidt and Claudia Kurrat and Mieczyslaw R. Gajda and Ansgar Malich and Rolf Br{\"a}uer and Werner A. Kaiser},
  journal={Investigative radiology},
  year={2004},
  volume={39 10},
  pages={
          626-32
        }
}
PURPOSE Near-infrared range fluorescence (NIRF) imaging is a potential tool to diagnose biologic processes in vivo. This applicability study sought to define whether imaging with fluorochrome Cy5.5 can identify arthritis in murine antigen-induced arthritis (AIA). MATERIALS AND METHODS On day 7 of AIA (n = 9 mice), fluorescence intensities in inflamed and contralateral knee joints (the latter as internal control) were measured before and after intravenous injection of Cy5.5 (until 72 hours… CONTINUE READING

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