Diagnosis of acid-base derangements and mortality prediction in the trauma intensive care unit: the physiochemical approach.

@article{Martin2005DiagnosisOA,
  title={Diagnosis of acid-base derangements and mortality prediction in the trauma intensive care unit: the physiochemical approach.},
  author={Matthew Jeffrey Martin and James Murray and Thomas V. Berne and Demetrios Demetriades and Howard Belzberg},
  journal={The Journal of trauma},
  year={2005},
  volume={58 2},
  pages={238-43}
}
BACKGROUND Conventional measures such as anion gap and base deficit can be inadequate for defining and managing complex acid-base derangements. Physiochemical analysis is an alternative approach based on the principles of electroneutrality and conservation of mass, and may be more accurate for defining the presence and type of acidosis and unmeasured anions. METHODS We retrospectively analyzed 2,152 sets of laboratory data from 427 trauma patients admitted to the intensive care unit. All data… CONTINUE READING

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