Diagnosis of Scrub Typhus

  title={Diagnosis of Scrub Typhus},
  author={Gavin C. K. W. Koh and Richard James Maude and Daniel H Paris and Paul Newton and Stuart D Blacksell},
  booktitle={The American journal of tropical medicine and hygiene},
Scrub typhus is transmitted by trombiculid mites and is endemic to East and Southeast Asia and Northern Australia. The clinical syndrome classically consists of a fever, rash, and eschar, but scrub typhus also commonly presents as an undifferentiated fever that requires laboratory confirmation of the diagnosis, usually by indirect fluorescent antibody (IFA) assay. We discuss the limitations of IFA, debate the value of other methods based on antigen detection and nucleic acid amplification, and… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 3 times. VIEW TWEETS


Publications citing this paper.
Showing 1-10 of 68 extracted citations

Scrub typhus

Indian journal of anaesthesia • 2013
View 4 Excerpts
Highly Influenced

Imported scrub typhus: first case in South America and review of the literature

Tropical diseases, travel medicine and vaccines • 2018
View 1 Excerpt

Kinetics of IgM and IgG antibodies after scrub typhus infection and the clinical implications

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases • 2018

Scrub Typhus – A Major Cause of Pediatric Intensive Care Admission and Multiple Organ Dysfunction Syndrome: A Single-Center Experience from India

Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine • 2018


Publications referenced by this paper.
Showing 1-10 of 18 references

A highly sensitive quantitative real-time PCR assay based on the groEL gene of contemporary Thai strains of Orientia tsutsugamushi

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases • 2009

Scrub typhus: the geographic distribution of phenotypic and genotypic variants of Orientia tsutsugamushi.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America • 2009

Clinical usefulness of eschar polymerase chain reaction for the diagnosis of scrub typhus : a prospective study

W Saisongkorn, M Chenchittikul, K Silpapojakul
Clin Infect Dis • 2006

Development of a quantitative real - time polymerase chain reaction assay specific for Orientia tsutsugamushi

DH Paris, N Aukkanit, K Jenjaroen, SD Blacksell, Day NPJ
Am J Trop Med Hyg • 2004

Similar Papers

Loading similar papers…