Diagnosis of Scrub Typhus

@inproceedings{Koh2010DiagnosisOS,
  title={Diagnosis of Scrub Typhus},
  author={Gavin C. K. W. Koh and Richard James Maude and Daniel H Paris and Paul Newton and Stuart D Blacksell},
  booktitle={The American journal of tropical medicine and hygiene},
  year={2010}
}
Scrub typhus is transmitted by trombiculid mites and is endemic to East and Southeast Asia and Northern Australia. The clinical syndrome classically consists of a fever, rash, and eschar, but scrub typhus also commonly presents as an undifferentiated fever that requires laboratory confirmation of the diagnosis, usually by indirect fluorescent antibody (IFA) assay. We discuss the limitations of IFA, debate the value of other methods based on antigen detection and nucleic acid amplification, and… CONTINUE READING
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