Diagnosis of Acanthamoeba keratitis in vivo with confocal microscopy.


We present eight cases of Acanthamoeba keratitis. In each case; the Acanthamoeba organisms were visualized in the epithelium and anterior stroma using tandem scanning confocal microscopy. The organisms were highly reflective, ovoid, and were 10-25 microns in diameter. The Acanthamoeba organisms in the human corneas were identical in size and shape to Acanthamoeba organisms on an agar plate visualized with the same confocal microscope. Confocal microscopy is a useful method for identifying Acanthamoeba organisms in vivo within the corneal epithelium and anterior stroma.


Citations per Year

164 Citations

Semantic Scholar estimates that this publication has 164 citations based on the available data.

See our FAQ for additional information.

Cite this paper

@article{Winchester1995DiagnosisOA, title={Diagnosis of Acanthamoeba keratitis in vivo with confocal microscopy.}, author={Kimberly S Winchester and William D. Mathers and John E. Sutphin and Tasha Daley}, journal={Cornea}, year={1995}, volume={14 1}, pages={10-7} }