Diagnosis and treatment of the solitary thyroid nodule. Results of a European survey

@article{Bennedbk1999DiagnosisAT,
  title={Diagnosis and treatment of the solitary thyroid nodule. Results of a European survey},
  author={Finn Noe Bennedb{\ae}k and Hans Perrild and Laszlo Heged{\"u}s},
  journal={Clinical Endocrinology},
  year={1999},
  volume={50}
}
The optimum diagnostic and therapeutic strategy for the euthyroid patient with a solitary thyroid nodule is still a matter of debate. The aim was to assess the attitudes towards management of such patients in clinical centres throughout Europe by means of a questionnaire. 
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The present study aimed to compare the sensitivity of this technique with serum calcitonin measurement and to assess the therapeutic implications of an inadequate preoperative diagnosis of sporadic medullary thyroid carcinoma.
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Evaluation of a thyroid nodule.
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A nonsurgical strategy prevails in North America, and despite controversies on the effect of L-T4, this treatment is supported by more than 40% in both Europe and North America.
Fate of the non‐operated, non‐toxic goitre in a defined population
There is lack of consensus in Europe regarding the management of patients with benign goitre. This study evaluated the long‐term results of recommending no surgery for clinically and cytologically
Frozen Section in a Cytological Diagnosis of Thyroid Follicular Neoplasm
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References

SHOWING 1-10 OF 20 REFERENCES
Ultrasound guided percutaneous ethanol injection in the treatment of cystic thyroid nodules
TLDR
The efficacy and safety of ultrasound guided percutaneous ethanol injection for the treatment of benign cystic thyroid nodules in euthyroid patients is examined.
Prevalence of sporadic medullary thyroid carcinoma: the importance of routine measurement of serum calcitonin in the diagnostic evaluation of thyroid nodules
TLDR
The prevalence of sporadic forms of medullary thyroid carcinoma has been studied in patients living in an area of moderate iodine deficiency and, in patients affected with the disease, the stage of the disease according to surgical findings and post surgical plasma CT levels is evaluated.
The management of differentiated thyroid cancer in Europe in 1988. Results of an international survey.
TLDR
Analysis of the 157 responses from thyroid experts showed that three in vitro tests (sensitive-TSH, free T4 and total T4) and three in vivo tests (99mTc or radioiodide scintiscan, fine needle aspiration and ultrasonography) were performed most frequently.
Ultrasonography in the evaluation of cold thyroid nodules.
TLDR
In the authors' catchment area of roughly 1 million inhabitants(tertiary referral centre) a diagnosis of thyroid malig-nancy is made in 20 patients each year, and because usually only 10 of these patients proves tohave thyroid malignancy, it is generally believed that therisk of thyroidmalignancy in a solitary nodule referred for diagnostic examination is approximately 2–5%.
AACE Clinical Practice Guidelines for the Diagnosis and Management of Thyroid Nodules
TLDR
The AACE Thyroid Guidelines clarify and emphasize the added value of the clinical endocrinologist in the diagnosis and management of thyroid nodules and outline a clear and concise state-of-the-art approach to Thyroid nodules.
Effectiveness of the thyroid scan in evaluation of the solitary thyroid nodule.
TLDR
Because thyroid scans add little in determining which nodules require surgical excision, they should no longer be a routine part of the evaluation of a solitary thyroid nodule.
Experience in a specialist thyroid surgery unit: a demographic study, surgical complications, and outcome.
TLDR
The decline in the number of operations for benignGoitre at Odense University Hospital parallels the increase it waiting time before operation, which can be explained by loss of operating room capacity rather than introduction of some alternative cure for goitre or change of criteria for operation.
Current evaluation of thyroid nodules
  • H. Gharib
  • Medicine
    Trends in Endocrinology & Metabolism
  • 1994
Effect of percutaneous ethanol injection therapy versus suppressive doses of L-thyroxine on benign solitary solid cold thyroid nodules: a randomized trial.
TLDR
The thyroid nodule-reducing effect of L-T4 suppressive therapy is insignificant, but a subjective satisfactory clinical response is seen in a subgroup of patients, probably explained by the concomitant reduction of perinodular thyroid volume.
...
...