Diagnosis and treatment of cardiac sarcoidosis

@article{Kusano2015DiagnosisAT,
  title={Diagnosis and treatment of cardiac sarcoidosis},
  author={K. Kusano and K. Satomi},
  journal={Heart},
  year={2015},
  volume={102},
  pages={184 - 190}
}
Sarcoidosis is a systemic granulomatous disease of unknown aetiology. The frequency of cardiac involvement (cardiac sarcoidosis (CS)) varies in the different geographical regions, but it has been reported that it is an absolutely important prognostic factor in this disease. Complete atrioventricular block is the most common, and ventricular tachycardia/ventricular fibrillation the second most common arrhythmia in this disease, both of which are associated with cardiac sudden death. Diagnosing… Expand
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References

SHOWING 1-10 OF 34 REFERENCES
Cardiac sarcoidosis: diagnosis and management
TLDR
The epidemiology, developments in diagnostic techniques and the management of cardiac sarcoidosis are reviewed, which relates to the heterogeneous nature of heart involvement and marked differences between racial groups. Expand
Isolated cardiac sarcoidosis: clinical characteristics, diagnosis and treatment.
TLDR
Current knowledge on the pathogenesis of sarcoidosis, clinical features of cardiac sarcoIDosis especially that isolated to the heart by showing some typical cases, and Utilities and problems of diagnostic imaging tests for this condition including echocardiography, cardiac magnetic resonance imaging, and fluorodeoxyglucose-positron emission tomography are discussed. Expand
Cardiac sarcoidosis.
TLDR
All patients diagnosed with sarcoidosis should be screened for cardiac involvement and patients with CS and symptoms such as syncope need an aggressive workup for a potentially life-threatening etiology, and often require implantable cardioverter-defibrillator therapy. Expand
Cardiac sarcoidosis: a comprehensive review
TLDR
Considering the increased risk of sudden death, cardiac sarcoidosis is an indication for early treatment with corticosteroids or other immunosuppressive agents, and in refractory cases, cardiac transplantation should be considered. Expand
Incidence of cardiac sarcoidosis in Japanese patients with high-degree atrioventricular block.
TLDR
The possibility of cardiac sarcoidosis should be carefully considered in middle-aged or elderly Japanese women who show high-degree atrioventricular block, most frequently in women aged 40 to 69 years. Expand
Clinical and Histopathological Profile of Sarcoidosis of the Heart and Acute Idiopathic Myocarditis Concepts through a study employing endomyocardial biopsy I. Sarcoidosis : Symposium on Secondary Myocardial Disease
TLDR
This communication reports the analysis of expanded case material, evaluation of endomyocardial biopsy in 8 biopsied and 7 autopsied cases, and the effects of steroid and pacemaker therapy on the nature of giant cell myocarditis. Expand
Relationship between arrhythmogenesis and disease activity in cardiac sarcoidosis.
TLDR
In cardiac sarcoidosis patients, CAVB develops mainly during the active phase of the disease, and early treatment with corticosteroids might improve AV conduction disturbance. Expand
Systematic Treatment Approach to Ventricular Tachycardia in Cardiac Sarcoidosis
TLDR
A systematic treatment approach to cardiac sarcoidosis with VT successfully suppressed VT recurrences in the majority of patients studied. Expand
Cardiac Sarcoidosis and Giant Cell Myocarditis as Causes of Atrioventricular Block in Young and Middle-Aged Adults
TLDR
CS and GCM explain ≥25% of initially unexplained AVB in young and middle-aged adults undergoing pacemaker implantation for AVB, and these patients are at high risk for adverse cardiac events. Expand
Effect of Corticosteroid Therapy on Long-Term Clinical Outcome and Left Ventricular Function in Patients With Cardiac Sarcoidosis.
TLDR
Corticosteroid therapy might have a beneficial effect on long-term clinical outcome in CS patients, particularly by reduction of heart failure admission and retarding the progression of LV systolic dysfunction. Expand
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