OBJECTIVE To analyze the diagnosis and treatment of brain tumors in jugular foramen region. METHODS 22 patients with brain tumor in jugular foramen region who had been diagnosed and treated from 1996 to 2000. Considerable literature was reviewed. RESULTS Tumor imaging technique showed masses of different shapes in unilateral jugular foramen region. All of the 22 patients underwent operation via different approaches. Total removal of the tumor was achieved in 20 patients and subtotal removal in 2. Pathological examination confirmed the diagnosis of neurinoma in 13 patients, tumor of glomus jugulare in 4, meningioma in 3, chordoma in 1, and metastatic tumor in 1. Only one patient died after operation. The mortality rate was as low as 4.5%. CONCLUSION The most common tumors in jugular foramen region are neurinoma, tumor of glomus jugulare, and meningioma. Surgery is effective in treatment of brain tumor in jugular foramen region.