Diagnosis and therapy of sporadic and familial medullary thyroid carcinoma

  title={Diagnosis and therapy of sporadic and familial medullary thyroid carcinoma},
  author={O Gimm and Thomas Sutter and Henning 5 Dralle},
  journal={Journal of Cancer Research and Clinical Oncology},
Medullary thyroid carcinoma (MTC) is a rare thyroid malignancy. About 75% are sporadic (sMTC) while the remaining 25% are hereditary (hMTC). The treatment of choice for both sMTC and hMTC is surgery. An adequate initial operation provides the best chance of cure. Hence, the diagnosis of MTC should be made preoperatively. In sMTC, ultrasound, ultrasound-guided fine-needle aspiration cytology and measurement of calcitonin levels (basal and after injection of calcitonin-stimulating reagents, e.g… CONTINUE READING


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