Diagnosis and prevention of chronic kidney allograft loss

  title={Diagnosis and prevention of chronic kidney allograft loss},
  author={B. Nankivell and D. Kuypers},
  journal={The Lancet},
  • B. Nankivell, D. Kuypers
  • Published 2011
  • Medicine
  • The Lancet
  • Kidney transplantation is the best possible treatment for many patients with end-stage renal failure, but progressive dysfunction and eventual allograft loss with return to dialysis is associated with increased mortality and morbidity. Immune injury from acute or chronic rejection and non-immune causes, such as nephrotoxicity from calcineurin inhibitors, ischaemia-reperfusion injury, recurrent glomerular disease, and allograft BK viral infection, are potential threats. Serial monitoring of… CONTINUE READING
    236 Citations
    Diagnosis and prevention of chronic kidney allograft loss
    • 3
    • Highly Influenced
    Chronic renal allograft dysfunction: risk factors, immunology and prevention.
    • 16
    Challenges and considerations in diagnosing the kidney disease in deteriorating graft function
    • H. Ekberg, M. Johansson
    • Medicine
    • Transplant international : official journal of the European Society for Organ Transplantation
    • 2012
    • 14
    • Highly Influenced
    Prevention of cardiovascular disease after renal transplantation
    • 26
    Recurrent Acute Kidney Injury in Renal Transplant Patients: A Single-Center Study.
    • 7
    • Highly Influenced
    Has the survival of the graft improved after renal transplantation in the era of modern immunosuppression?
    • 23
    Eculizumab in renal transplantation.
    • 40


    The natural history of chronic allograft nephropathy.
    • 942
    • PDF
    Chronic renal failure after transplantation of a nonrenal organ.
    • 1,437
    • PDF
    The kidney transplant: new horizons
    • M. Mengel
    • Medicine
    • Current opinion in nephrology and hypertension
    • 2010
    • 11
    Optimizing medication adherence: an ongoing opportunity to improve outcomes after kidney transplantation.
    • 119
    • PDF
    A primer on recurrent and de novo glomerulonephritis in renal allografts
    • B. Iványi
    • Medicine
    • Nature Clinical Practice Nephrology
    • 2008
    • 67
    A molecular classifier for predicting future graft loss in late kidney transplant biopsies.
    • 142
    • PDF