Diagnosis and management of type I and type V hyperlipoproteinemia.

  title={Diagnosis and management of type I and type V hyperlipoproteinemia.},
  author={Takanari Gotoda and Koji Shirai and Takao Ohta and Junji Kobayashi and Shinji Yokoyama and Shinichi Oikawa and Hideaki Bujo and Shun Ishibashi and Hidenori Arai and Shizuya Yamashita and Mariko Harada-Shiba and Masaaki Eto and Toshio Hayashi and Hirohito Sone and Hiroaki Suzuki and Nobuhiro Yamada},
  journal={Journal of atherosclerosis and thrombosis},
  volume={19 1},
Both type I and type V hyperlipoproteinemia are characterized by severe hypertriglyceridemia due to an increase in chylomicrons. Type I hyperlipoproteinemia is caused by a decisive abnormality of the lipoprotein lipase (LPL)- apolipoprotein C-II system, whereas the cause of type V hyperlipoproteinemia is more complicated and more closely related to acquired environmental factors. Since the relationship of hypertriglyceridemia with atherosclerosis is not as clear as that of hypercholesterolemia… CONTINUE READING


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