Diagnosis and management of the adolescent boy with Klinefelter syndrome.

@article{Manning2002DiagnosisAM,
  title={Diagnosis and management of the adolescent boy with Klinefelter syndrome.},
  author={Melanie A. Manning and H. Eugene Hoyme},
  journal={Adolescent medicine},
  year={2002},
  volume={13 2},
  pages={367-74, viii}
}
Klinefelter syndrome is the most common sex chromosome disorder, affecting approximately 1/500 to 1/1000 males. The condition results when one or more extra X chromosomes are present in the cells of XY fetuses. Although the clinical presentation is variable, all males with Klinefelter syndrome demonstrate hypogonadism, impaired spermatogenesis, and androgen deficiency. Treatment options include testosterone replacement for correction of the androgen deficiency and tailoring of school curricula… CONTINUE READING