Diagnosis and management of subclinical hypothyroidism in pregnancy

  title={Diagnosis and management of subclinical hypothyroidism in pregnancy},
  author={R. Negro and A. Stagnaro-Green},
  journal={BMJ : British Medical Journal},
  • R. Negro, A. Stagnaro-Green
  • Published 2014
  • Medicine
  • BMJ : British Medical Journal
  • In prospective studies, the prevalence of undiagnosed subclinical hypothyroidism in pregnant women ranges from 3% to 15%. Subclinical hypothyroidism is associated with multiple adverse outcomes in the mother and fetus, including spontaneous abortion, pre-eclampsia, gestational hypertension, gestational diabetes, preterm delivery, and decreased IQ in the offspring. Only two prospective studies have evaluated the impact of levothyroxine therapy in pregnant women with subclinical hypothyroidism… CONTINUE READING
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