Diagnosis and management of scleroderma peripheral vascular disease.

  title={Diagnosis and management of scleroderma peripheral vascular disease.},
  author={Ariane L. Herrick},
  journal={Rheumatic diseases clinics of North America},
  volume={34 1},
  pages={89-114; vii}
The manifestations of peripheral vascular disease in patients who have systemic sclerosis (SSc) range from episodic Raynaud's phenomenon to irreversible tissue injury with ulceration and gangrene. Structural and functional changes may occur in the microvessels, digital arteries, and sometimes more proximal vessels. This article discusses the assessment of patients who have Raynaud's phenomenon in whom an underlying scleroderma-spectrum disorder is suspected and patients who have SSc with… CONTINUE READING