Diagnosis and management of lower limb peripheral arterial disease: summary of NICE guidance

@article{Layden2012DiagnosisAM,
  title={Diagnosis and management of lower limb peripheral arterial disease: summary of NICE guidance},
  author={Jennifer E. Layden and Jonathan Anthony Michaels and Sarah L Bermingham and Bernard G Higgins},
  journal={BMJ : British Medical Journal},
  year={2012},
  volume={345}
}
Lower limb peripheral arterial disease (referred to as peripheral arterial disease in this summary) is common, affecting 3% to 7% of people in the general population and 20% of people over the age of 75.1 It is associated with an increased risk of cardiovascular morbidity and mortality and severely limits people’s functional capacity and quality of life. Peripheral arterial disease is often asymptomatic, but when it is symptomatic the most common presentation is intermittent claudication (pain… Expand
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References

SHOWING 1-10 OF 42 REFERENCES
Incidence, natural history and cardiovascular events in symptomatic and asymptomatic peripheral arterial disease in the general population.
TLDR
Subjects with asymptomatic peripheral arterial disease appear to have the same increased risk of cardiovascular events and death found in claudicants. Expand
Low recognition of post-traumatic stress disorder in primary care
TLDR
The Improving Access to Psychological Therapies (IAPT) programme will make the NICE recommended treatments more widely available and will allow self-referral by adults with PTSD to trauma-focused psychological therapy. Expand
Epidemiology of anxiety disorders.
TLDR
The overall prevalence of anxiety disorders is shown to be quite high, but with considerable variation from the most prevalent (specific phobias) to the least prevalent (agoraphobia without a history of panic disorder) disorders. Expand
A guide to guidelines for the treatment of PTSD and related conditions.
TLDR
The aim of this article is to examine the various guidelines and to compare and contrast their methodologies and recommendations to aid clinicians in making decisions about their use. Expand
Prevalence of mental disorders and psychosocial impairments in adolescents and young adults.
TLDR
Findings underline that mental disorders in young adults are frequent and impairing, limiting work and education ability and social interaction, and indicate a considerable risk potential for an accumulation of complicating factors and future chronicity. Expand
Vascular Society of Great Britain and Ireland
The following abstracts are from papers presented at the prize sessions of the 42nd annual scientific meeting of the Vascular Society of Great Britain and Ireland, held in Manchester on 28th–30thExpand
Post-traumatic stress disorder: findings from the Australian National Survey of Mental Health and Well-being
TLDR
R rape and sexual molestation were the traumatic events most likely to be associated with PTSD, and a high level of Axis 1 co-morbidity was found among those persons with PTSD. Expand
The British Child and Adolescent Mental Health Survey 1999: the prevalence of DSM-IV disorders.
TLDR
Roughly 1 in 10 children have at least one DSM-IV disorder, involving a level of distress or social impairment likely to warrant treatment, and comorbidity reported between some childhood diagnoses may be due to the association of both disorders with a third. Expand
Prevalence of serious mental disorder in 7000 refugees resettled in western countries: a systematic review
TLDR
Refugees resettled in western countries could be about ten times more likely to have post-traumatic stress disorder than age-matched general populations in those countries. Expand
National Institute for Health and Clinical Excellence
The economic model enclosed and its contents are confidential and are protected by intellectual property rights, which are owned by the Centre for Reviews and Dissemination/Centre for HealthExpand
...
1
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3
4
5
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