Diagnosis and immunophenotype of 188 pediatric lymphoblastic lymphomas treated within a randomized prospective trial: experiences and preliminary recommendations from the European childhood lymphoma pathology panel.

@article{Oschlies2011DiagnosisAI,
  title={Diagnosis and immunophenotype of 188 pediatric lymphoblastic lymphomas treated within a randomized prospective trial: experiences and preliminary recommendations from the European childhood lymphoma pathology panel.},
  author={I Oschlies and Birgit Burkhardt and Catherine Chassagne-Cl{\'e}ment and Emanuel S d'Amore and Ulrika Peetz Hansson and Konnie M. Hebeda and Keith Mc Carthy and R. Kodet and Jadwiga Maldyk and Leonhard M{\"u}llauer and Anna A Porwit and Ana-Iris Schmatz and Marianne Tinguely and Dimitry Abramov and Andrew Wotherspoon and Martin Zimmermann and A. Reiter and Wolfram Klapper},
  journal={The American journal of surgical pathology},
  year={2011},
  volume={35 6},
  pages={836-44}
}
The majority of lymphoblastic (precursor cell) neoplasms presents as leukemias. Consequently, the guidelines for lineage determination and subtyping of precursor cell neoplasms were primarily established for flow cytometry methods. Large-scale studies of nonleukemic lymphoblastic lymphomas are lacking so far. We analyzed a large series of pediatric patients with lymphoblastic lymphoma treated within a prospective randomized trial (the Euro-LB 02 study). Among 193 lymphomas, in which a detailed… CONTINUE READING

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