Diagnosis and Therapeutic Management of Extra-Intestinal Manifestations of Inflammatory Bowel Disease
@article{Trikudanathan2012DiagnosisAT, title={Diagnosis and Therapeutic Management of Extra-Intestinal Manifestations of Inflammatory Bowel Disease}, author={Guru Trikudanathan and Preethi G. K. Venkatesh and Udayakumar Navaneethan}, journal={Drugs}, year={2012}, volume={72}, pages={2333-2349} }
Extra-intestinal manifestations (EIMs) are reported frequently in patients with inflammatory bowel disease (IBD) and may be diagnosed before, concurrently or after the diagnosis of IBD. EIMs in IBD may be classified based on their association with IBD disease activity. The first group has a direct relationship with the activity of the bowel disease and includes pauciarticular arthritis, oral aphthous ulcers, erythema nodosum and episcleritis. The second group of EIMs appears to follow an…
76 Citations
Extraintestinal Manifestations of Inflammatory Bowel Disease: Current Concepts, Treatment, and Implications for Disease Management.
- MedicineGastroenterology
- 2021
In general, peripheral arthritis, oral aphthous ulcers, episcleritis, or erythema nodosum may be associated with active intestinal inflammation and may improve upon standard treatment of the intestinal inflammation.
Extraintestinal Manifestations of Inflammatory Bowel Disease
- MedicineInflammatory bowel diseases
- 2015
Extraintestinal manifestations in inflammatory bowel disease (IBD) are frequent and may occur before or after IBD diagnosis, and successful therapy of EIM is essential for improving quality of life of patients with IBD.
Extra-Intestinal Manifestations of Inflammatory Bowel Disease
- MedicineCureus
- 2021
The research scrutinizes the identified pathogenic mechanisms that tend to involve genetic susceptibility, aberrant self-recognition, and autoantibodies directed against organ-specific antigens shared by intestinal and extra-intestinal organs.
Skin Manifestations of Inflammatory Bowel Disease
- MedicineClinical Reviews in Allergy & Immunology
- 2017
Current knowledge on cutaneous EIMs, their diagnostic criteria and clinical presentation, natural history, pathogenesis, and treatment options are summarized.
Extra-intestinal Manifestations in Inflammatory Bowel Disease: Diagnosis and Management
- MedicineBiomarkers in Inflammatory Bowel Diseases
- 2019
There is a need for effective biomarkers in this area as there are none available and while biomarkers are used for related rheumatological conditions, they are not effective as diagnostic or prognostic markers for extra-intestinal manifestations of IBD.
Oral Manifestations of Inflammatory Bowel Disease and the Role of Non-Invasive Surrogate Markers of Disease Activity
- MedicineMedicines
- 2020
Fecal calprotectin is a non-invasive marker of intestinal inflammation and may be used to select which patients need to undergo endoscopic examination, thereby avoiding unnecessary investigations.
Oral manifestation in inflammatory bowel disease: a review.
- MedicineWorld journal of gastroenterology
- 2013
Oral manifestations of inflammatory bowel diseases, including Crohn's disease (CD) and ulcerative colitis, not only affect the intestinal tract but also have an extraintestinal involvement within the oral cavity, which may assist in the diagnosis and the monitoring of disease activity.
Occurrence of skin manifestations in patients of the Swiss Inflammatory Bowel Disease Cohort Study
- MedicinePloS one
- 2019
The results suggest that young females with a positive family history of IBD might be at increased risk for the onset of skin manifestations and require a careful screening for such complications.
Extraintestinal Manifestations of Inflammatory Bowel Disease
- MedicinePeriodic and Non-Periodic Fevers
- 2019
This chapter provides comprehensive review of various extraintestinal manifestations associated with IBD with specific focus on autoinflammation.
The Risk of Later Diagnosis of Inflammatory Bowel Disease in Patients With Dermatological Disorders Associated With Inflammatory Bowel Disease.
- MedicineInflammatory bowel diseases
- 2021
Younger age, smoking, low body mass index, anemia, and lower gastrointestinal symptoms were associated with an increased risk of diagnosis of IBD within 3 years in patients with EN, and patients with psoriasis had a 34% increased risk.
References
SHOWING 1-10 OF 111 REFERENCES
Extraintestinal manifestations of inflammatory bowel disease.
- MedicineDigestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
- 2008
Extraintestinal manifestations of inflammatory bowel disease.
- Medicine, BiologyMinerva gastroenterologica e dietologica
- 2005
It is important to acquire knowledge on these extraintestinal manifestations of Crohn's disease and ulcerative colitis to start the respective treatment early and represent just association between different syndromes of autoimmune etiology.
Management of extraintestinal manifestations and other complications of inflammatory bowel disease
- MedicineCurrent gastroenterology reports
- 2004
The epidemiology of primary sclerosing cholangitis (PSC), and its relationship to IBD, is becoming clearer, and Observational studies suggest that prolonged use of aminosalicylates is associated with decreased risk of neoplasia, but data are conflicting.
Rare extraintestinal manifestations of inflammatory bowel disease.
- MedicineInflammatory bowel diseases
- 2004
This review focuses on rare extraintestinal manifestations of IBD, which may formally be divided in rarely occurring alterations in frequently involved organ systems and rarely affected organ systems.
Uveitis and erythema nodosum in inflammatory bowel disease: clinical features and the role of HLA genes.
- Medicine, BiologyGastroenterology
- 2002
EN, uveitis, and arthritis associated with IBD occur together commonly and are associated with genes in the HLA region, and linkage disequilibrium between these genes may account for the clinical picture of overlapping but independent clinical manifestations.
Inflammatory bowel disease: complications and extraintestinal manifestations.
- MedicineDrugs of today
- 2009
Inflammatory bowel disease (IBD) is a disorder driven by immune dysregulation, characterized by a relapsing-remitting pattern which is punctuated by flares associated with abdominal pain and bloody…
The lung in inflammatory bowel disease.
- MedicineMedicine
- 1993
The data of an ongoing Registry containing 33 cases (23 cases receiving no drug therapy) with ulcerative colitis or, less often, Crohn's disease, who developed varied bronchopulmonary problems are reported.
Development of extraintestinal manifestations in pediatric patients with inflammatory bowel disease
- MedicineInflammatory bowel diseases
- 2009
The incidence of Extraintestinal manifestations in pediatric patients with inflammatory bowel disease differs by type of EIM and may be slightly higher in girls, but is independent of the type of IBD, age at diagnosis, and race/ethnicity.
The prevalence of extraintestinal diseases in inflammatory bowel disease: a population-based study
- MedicineAmerican Journal of Gastroenterology
- 2001
The associations of immune mediated diseases in extraintestinal sites may help to further the understanding of IBD pathogenesis, and it may help in developing a paradigm of disease subsets.
Immune-related systemic manifestations of inflammatory bowel disease. A prospective study of 792 patients.
- MedicineJournal of clinical gastroenterology
- 1996
Bowel-related systemic manifestations appeared frequently together in the same patient and patients with any of these manifestations ran a higher risk of developing another one, and autoimmune manifestations were associated with both Crohn's disease and ulcerative colitis.