Diagnosis and Monitoring of Chronic Myeloid Leukemia: Chiang Mai University Experience.
@article{Tantiworawit2016DiagnosisAM, title={Diagnosis and Monitoring of Chronic Myeloid Leukemia: Chiang Mai University Experience.}, author={A. Tantiworawit and Supanat Kongjarern and E. Rattarittamrong and S. Lekawanvijit and Kanokkan Bumroongkit and N. Boonma and Thanawat Rattanathammethee and Sasinee Hantrakool and Chatree Chai-Adisaksopha and L. Norasetthada}, journal={Asian Pacific journal of cancer prevention : APJCP}, year={2016}, volume={17 4}, pages={ 2159-64 } }
BACKGROUND
A diagnosis of chronic myeloid leukemia (CML) is made on discovery of the presence of a Philadelphia (Ph) chromosome. The success of the treatment of this form of leukemia with tyrosine kinase inhibitor (TKI) is monitored by reduction of the Ph chromosome.
OBJECTIVE
To compare the role of conventional cytogenetic (CC) methods with a real time quantitative polymerase chain reaction (RQ-PCR) and fluorescence in situ hybridization (FISH) for diagnosis and treatment monitoring of CML… CONTINUE READING
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